How do these medications work for weight loss?

Medications like Semaglutide and Tirzepatide are designed to help with weight loss by mimicking natural hormones in the body that regulate appetite and food intake. Semaglutide, for example, works by activating GLP-1 (glucagon-like peptide-1) receptors, which help reduce hunger, regulate blood sugar, and slow down digestion. This leads to reduced calorie intake and gradual weight loss. Tirzepatide has a similar mechanism, but it also targets GIP (gastric inhibitory polypeptide) receptors, making it even more effective for both blood sugar control and weight loss. Both medications have shown promising results in clinical trials for long-term weight management.

Updated on: 30/07/2025